Myeloproliferative Neoplasms 2010


This succinct resource provides an ideal
balance of the biology and practical therapeutic strategies for classic
and non-classic BCR-ABL-negative myeloproliferative neoplasms.  
Utilizing current World Health Organization nomenclature,
classification, and diagnostic criteria, international experts have
assembled to convey the most up-to-date knowledge in this rapidly
evolving field.  The opening chapters cover the diagnosis and
classification, genetics, cytogenetic findings, and prognostic factors
of MPNs.  Further chapters explore therapies specific to the different
disease entities, including polycythemia vera, essential
thrombocytopenia, myelofibrosis, and eosinophilic disorders, and
mastocytosis.  Unique areas of discussion include JAK2 inhibitor
therapy, hematopoietic stem cell transplantation, and blastic
transformation.  A valuable reference for practicing hematologists, this
forefront book enriches our understanding of recent discoveries and
their impact on conventional and investigational treatments

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