ISBN-13 / EAN: 9780123742476
Product Description: Many hundreds of thousands suffer spinal cord injuries leading to loss
of sensation and motor function in the body below the point of injury.
Spinal cord research has made some significant strides towards new
treatment methods, and is a focus of many laboratories worldwide. In
addition, research on the involvement of the spinal cord in pain and the
abilities of nervous tissue in the spine to regenerate has
increasingly been on the forefront of biomedical research in the past
years. The Spinal Cord, a collaboration with the Christopher and Dana
Reeve Foundation, is the first comprehensive book on the anatomy of the
mammalian spinal cord. Tens of thousands of articles and dozens of
books are published on this subject each year, and a great deal of
experimental work has been carried out on the rat spinal cord. Despite
this, there is no comprehensive and authoritative atlas of the mammalian
spinal cord. Almost all of the fine details of spinal cord anatomy
must be searched for in journal articles on particular subjects. This
book addresses this need by providing both a comprehensive reference on
the mammalian spinal cord and a comparative atlas of both rat and
mouse spinal cords in one convenient source. The book provides a
descriptive survey of the details of mammalian spinal cord anatomy,
focusing on the rat with many illustrations from the leading experts in
the field and atlases of the rat and the mouse spinal cord. The rat
and mouse spinal cord atlas chapters include photographs of Nissl
stained transverse sections from each of the spinal cord segments
(obtained from a single unfixed spinal cord), detailed diagrams of each
of the spinal cord segments pictured, delineating the laminae of Rexed
and all other significant neuronal groupings at each level and
photographs of additional sections displaying markers such as
acetylcholinesterase (AChE), calbindin, calretinin, choline
acetlytransferase, neurofilament protein (SMI 32), enkephalin,
calcitonin gene-related peptide (CGRP), and neuronal nuclear protein
(NeuN).
The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements.
The major topics addressed are:
. development of the spinal cord
. the gross anatomy of the spinal cord and its meninges
. spinal nerves, nerve roots, and dorsal root ganglia
. the vertebral column, vertebral joints, and vertebral muscles
. blood supply of the spinal cord
. cytoarchitecture and chemoarchitecture of the spinal gray matter
. musculotopic anatomy of motoneuron groups
. tracts connecting the brain and spinal cord
. spinospinal pathways
. sympathetic and parasympathetic elements in the spinal cord
. neuronal groups and pathways that control micturition
. the anatomy of spinal cord injury in experimental animals
The atlas of the rat and mouse spinal cord has the following features:
. Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse.
. Detailed diagrams of each of the 34 spinal segments for rat and mouse,
delineating the laminae of Rexed and all other significant neuronal
groupings at each level.
. Alongside each of the 34 Nissl stained segments, there are additional
sections displaying markers such as acetylcholinesterase, calbindin,
calretinin, choline acetlytransferase, neurofilament protein (SMI 32),
and neuronal nuclear protein (NeuN).
. All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply.
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Subject: The Spinal Cord: A Christopher and Dana Reeve Foundation Text and Atlas 
Mon Mar 28, 2011 8:40 am
